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Is There a COVID Vaccine / Cancer Connection? Multiple sources in The HighWire's network of frontline physicians, have reported an alarming uptick in aggressive cancers post-COVID vaccination. Could there be a link? A recent article may explain the increase in cancer cases. It starts with the work of doctors Katalin Karikó and Drew Weissman, who invented the nucleoside modification technology that protects mRNA from the body's immune defenses by destroying the alarm signal of the Innate Immune System, known as the Toll Like Receptors (TLR). These findings were adopted in the mRNA technology used in COVID vaccines, in order that the foreign vaccine mRNA could enter cells without being destroyed. But shutting down your immune response in order to deliver a vaccine might not be such a great idea after all, since these Toll Like Receptors are what alert the body to the presence of antigens, including bacteria, viruses and cancer cells, to trigger the immune response. This may explain the high number of shingles outbreaks in the vaccinated, although specific mechanisms are still unclear. The article concludes: "Changes to key parts of the mRNA code in SARS-CoV-2 vaccines may be causal in changing the innate immune response via toll-like receptors. Toll-like receptors are important components in defence against infection and downstream effects may also include inhibition of CD8 T cell response. CD8 is a vital part of the immune system’s ability to eradicate infection and cancer...Anecdotal reports of significant uptick in cancer presenting to medical consultants may be consistent with aberrant toll-like receptor and dendritic cell changes leading to an inhibition of the anti-cancer CD8 effector response. Further data are required but the prospect of an altered CD8 response to infection and cancer is very concerning and should prompt urgent investigation." Pathologist, Dr Ryan Cole is cited in the article stating that he is observing a 20X uptick in endometrial cancer, and increases in other cancers post-SARS-CoV-2 vaccination. He joins Del Bigtree to discuss the available science and his lab's findings. Running Time: 27 minutes

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