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African trypanosomes, sleeping Sickness--Think Morgellons

Posted By: CrystalRiver
Date: Thursday, 13-Apr-2023 02:17:45
www.rumormill.news/220730

https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-019-3355-5

Conclusions
Trypanosomes continue to provide important insights to the evolution of eukaryotic cells, while remaining significant pathogens in sub-Saharan Africa. In combination, this makes the continued analysis of trypanosome biology compelling. With respect to fundamental biology, the unusual kinetochore composition in trypanosomatids has gained significant interest in the wider cell biology community, as has their unique mitochondrial biology and flagellar dynamics. Significant progress has also been made in therapeutics for these parasites, with several compounds at different stages of the drug development pipeline, most notably fexinidazole [109] and oxaboroles [110]. This has resulted from significant investment in the discovery of small molecule therapeutics which offer oral delivery and reduced toxicity. Similarly, the innovations in gene technology, including high throughput genetic screens, comprehensive protein localisation approaches ([111] http://tryptag.org) and the application of CRISPR technology to laboratory adapted and developmentally competent trypanosome lines have accelerated understanding of the parasite’s biology whilst helping the prediction of how drug resistance might emerge to new therapies. The first golden age of trypanosome biology was in the 1900s when the disease agent and vector was identified, and the second was in the 1980s and early 1990s where the unusual molecular mechanisms of trypanosomes were uncovered, particularly in relation to antigenic variation. We are currently in the third golden age, where this molecular understanding is applied to the fascinating biology of the parasite in the host and in the field, and for the discovery of new therapies.

--------------------------------------------------
Dear RM Agents and Readers,

I have spoke of African Sleeping sickness here at Rumormllnews I think it was before the take down of Rumormillnews.

This is most likely what has contributed to that known as morgellons. Marble, Colorado was the best I ever felt and that was what was taken from me when I had to move, my health. I'm better now but am able to tell you that I felt so much better when I lived there, less the last 3 years.

Those with Morgellons have always known they feel better if not nearby a cell phone and or computer.

Many Blessings,
CrystalRiver




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  • African trypanosomes, sleeping Sickness--Think Morgellons
    CrystalRiver -- Thursday, 13-Apr-2023 02:17:45

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