There is also another two-actor "Who's On First" parody that was uploaded to YouTube in 2020 that put the comedy emphasis on the word, WHO. I wasn't as impressed with that video parody, while the following script focuses on the vaccinated vs. unvaccinated controversy that is much more relevant for today's audiences.
-NW

If Abbott and Costello Were Around Today This Would be the Updated Version Of “Who’s On First”
Kev Spirited
Right Wire Report
Aug 16, 2021

Bud: ‘You can’t come in here!’
Lou: ‘Why not?’
Bud: ‘Well because you’re unvaccinated.’
Lou: ‘But I’m not sick.’

Bud: ‘It doesn’t matter.’
Lou: ‘Well, why does that guy get to go in?’
Bud: ‘Because he’s vaccinated.’
Lou: ‘But he’s sick!’
Bud: ‘It’s alright. Everyone in here is vaccinated.’
Lou: ‘Wait a minute. Are you saying everyone in there is vaccinated?’
Bud: ‘Yes.’
Lou: ‘So then why can’t I go in there if everyone is vaccinated?’
Bud: ‘Because you’ll make them sick.’
Lou: ‘How will I make them sick if I’m NOT sick and they’re vaccinated.’
Bud: ‘Because you’re unvaccinated.’
Lou: ‘But they’re vaccinated.’
Bud: ‘But they can still get sick.’
Lou: ‘So what the heck does the vaccine do?’
Bud: ‘It vaccinates.’
Lou: ‘So vaccinated people can’t spread covid?’
Bud: ‘Oh no. They can spread covid just as easily as an unvaccinated person.’
Lou: ‘I don’t even know what I’m saying anymore. Look. I’m not sick.
Bud: ‘Ok.’
Lou: ‘And the guy you let in IS sick.’
Bud: ‘That’s right.’
Lou: ‘And everybody in there can still get sick even though they’re vaccinated.’
Bud: ‘Certainly.’
Lou: ‘So why can’t I go in again?’
Bud: ‘Because you’re unvaccinated.’
Lou: ‘I’m not asking who’s vaccinated or not!’
Bud: ‘I’m just telling you how it is.’
Lou: ‘Nevermind. I’ll just put on my mask.’
Bud: ‘That’s fine.’
Lou: ‘Now I can go in?’
Bud: ‘Absolutely not?’
Lou: ‘But I have a mask!’
Bud: ‘Doesn’t matter.’
Lou: ‘I was able to come in here yesterday with a mask.’
Bud: ‘I know.’
Lou: So why can’t I come in here today with a mask? ….If you say ‘because I’m unvaccinated’ again, I’ll break your arm.’
Bud: ‘Take it easy buddy.’
Lou: ‘So the mask is no good anymore.’
Bud: ‘No, it’s still good.’
Lou: ‘But I can’t come in?’
Bud: ‘Correct.’
Lou: ‘Why not?’
Bud: ‘Because you’re unvaccinated.’
Lou: ‘But the mask prevents the germs from getting out.’
Bud: ‘Yes, but people can still catch your germs.’
Lou: ‘But they’re all vaccinated.’
Bud: ‘Yes, but they can still get sick.’
Lou: ‘But I’m not sick!!’
Bud: ‘You can still get them sick.’
Lou: ‘So then masks don’t work!’
Bud: ‘Masks work quite well.’
Lou: ‘So how in the heck can I get vaccinated people sick if I’m not sick and masks work?’
Bud: ‘Third base.’