https://www.dovepress.com/reframing-delusional-infestation-perspectives-on-unresolved-puzzles-peer-reviewed-fulltext-article-PRBM

Reframing delusional infestation: perspectives on unresolved puzzles (morgellons,cr)

Authors Lai JB, Xu Z, Xu Y, Hu SH

Received 27 February 2018

Accepted for publication 19 July 2018

Published 1 October 2018 Volume 2018:11 Pages 425—432

DOI https://doi.org/10.2147/PRBM.S166720

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Professor Igor Elman

Article has an altmetric score of 4

Jianbo Lai,1–3 Zhe Xu,4,5 Yi Xu,1–3 Shaohua Hu1–3

1Department of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China; 2The Key Laboratory of Mental Disorder’s Management in Zhejiang Province, Hangzhou 310003, China; 3Brain Research Institute of Zhejiang University, Hangzhou 310003, China; 4Zhejiang University School of Medicine, Hangzhou 310003, China; 5Department of Psychiatry, Third People’s Hospital of Huzhou, Hangzhou 313000, China

Abstract: Delusional infestation (DI), a debilitating psychocutaneous condition, featured as a false fixed belief of being infested accompanied by somatosensory abnormality, behavior alteration, and cognitive impairment. Although management of primary causes and pharmacotherapy with antipsychotics and/or antidepressants can help to alleviate symptoms in most patients, the underlying etiology of DI still remains unclear. Morgellons disease (MD), characterized by the presence of cutaneous filaments projected from or embedded in skin, is also a polemic issue because of its relationship with spirochetal infection. This review aims to discuss the following topics that currently confuse our understandings of DI: 1) the relationship of real/sham “infestation” with DI/MD; 2) behavior alterations, such as self-inflicted trauma; 3) neuroimaging abnormality and disturbance in neurotransmitter systems; and 4) impaired insight in patients with this disease. In discussion, we try to propose a multifactorial approach to the final diagnosis of DI/MD. Future studies exploring the neurobiological etiology of DI/MD are warranted.

Keywords: delusional infestation, Morgellons disease, behavior, neurotransmitter, insight

Introduction

Delusional infestation (DI) is an uncommon, intricate psychocutaneous condition.1 Against available medical evidence, patients with DI have a strong conviction that they are infested with little animals or less frequently inanimate matter.1,2 Meanwhile, patients always complain of abnormal skin sensations, such as stinging, biting, and crawling, which were ascribed to the “infestation”. The symptoms of DI can occur as primary, or more commonly, secondary to diverse medical conditions, such as neuropsychiatric diseases, nutrient deficiency, psychotropic medications, infections, intoxication, tumors, and metabolic disturbance.3 Etiology-dependent management and antipsychotics/antidepressants have been reported to be therapeutically effective.1,3,4

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Dear RM Agents and Readers,

What the American studies discovered was that the antipsychotics and antidepressants just muddled the water and didn't help the issue.

If I locate will post that article after this one later today.

My problem is with the Chinese Communist government not the people of China. The horror stories I have heard from the mouths of people of China frames some of my belief and concerns for this government. Persecuted, murdered for religious beliefs, you want to foll the communist ideology fine but America those that wish to practice the spiritual have that right!

Communism is not encompassing it is very myopic.

Many Blessings,
CrystalRiver