Probably not actually the end of physics as we know it. It's just time to fire up the Kluj-O-Matic Standard Model Tweaker.

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New LHC results suggest there's a flaw in the standard model of physics
Is this the end of physics as we know it?
FIONA MACDONALD - 10 MAR 2016

Recent results from the Large Hadron Collider (LHC) in Switzerland hint at activity going on beyond the standard model of particle physics - which means we could finally be about to enter a new era in physics.

Right now, the standard model is the best explanation we have for how the Universe works and how it's held together. But there are big gaps - most noticeably, the fact that the model doesn't actually account for gravity - so scientists have spent decades probing the boundaries of physics for signs of any activity that the standard model can't explain. And now they've found one.

The discrepancy deals with a particle called the B meson. According to the standard model, B mesons should decay at very specific angles and frequencies - but those predictions don't match up what's been seen in LHC experiments, suggesting that something else is going on. And if we can figure out what that is, it'll take us closer to unlocking some of the mysteries in our Universe.

"Up to now all measurements match the predictions of the standard model," said lead researcher Mariusz Witek, from the Institute of Nuclear Physics of the Polish Academy of Sciences. "However, we know that the standard model cannot explain all the features of the Universe. It doesn’t predict the masses of particles or tell us why fermions are organised in three families. How did the dominance of matter over antimatter in the universe come about? What is dark matter? Those questions remain unanswered."

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http://www.sciencealert.com/the-latest-lhc-findings-hint-at-strange-physics-beyond-the-standard-model