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Canine Filamentous Dermatitis Associated with Borrelia Infection

Posted By: CrystalRiver
Date: Wednesday, 13-Jan-2021 05:52:35
www.rumormill.news/89137

In Response To: Morgellons disease: a filamentous borrelial dermatitis (CrystalRiver)

Canine Filamentous Dermatitis Associated with Borrelia Infection

Research Article, J Vet Sci Med Diagn Vol: 5 Issue: 6

Canine Filamentous Dermatitis Associated with Borrelia Infection

Marianne J Middelveen1, Gheorghe M Rotaru2, Jody L McMurray2, Katherine R Filush3, Eva Sapi3, Jennie Burke4, Agustin Franco4, Lorenzo Malquori4, Melissa C McElroy1 and Raphael B Stricker1*
1International Lyme and Associated Diseases Society, Bethesda, Maryland, USA
2Heartland Veterinary Clinic, Airdrie, Alberta, Canada
3Department of Biology and Environmental Science, University of New Haven, West Haven, Connecticut, USA
4Australian Biologics, Sydney, New South Wales, Australia
Corresponding author : Raphael B
Stricker, M.D, International Lyme and Associated Diseases Society, Bethesda, Maryland, USA


Tel: +(415) 399- 1035
Fax: (415) 399-1057
E-mail: rstricker@usmamed.com
Received: September 12, 2016 Accepted: September 28, 2016 Published: October 03, 2016
Citation: Middelveen MJ, Rotaru GM, McMurray JL, Filush KR, Sapi E, et al. (2016) Canine Filamentous Dermatitis Associated with Borrelia Infection. J Vet Sci Med Diagn 5:6. doi: 10.4172/2325-9590.1000212
Abstract
Canine Filamentous Dermatitis Associated with Borrelia Infection

Background: Although canine clinical manifestations of Lyme disease vary widely, cutaneous manifestations are not well documented in dogs. In contrast, a variety of cutaneous manifestations are reported in human Lyme disease caused by the spirochete Borrelia burgdorferi. A recently recognized dermopathy associated with tickborne illness known as Morgellons disease is characterized by brightly-colored filamentous inclusions and projections detected in ulcerative lesions and under unbroken skin. Recent studies have demonstrated that the dermal filaments are collagen and keratin biofibers produced by epithelial cells in response to spirochetal infection. We now describe a similar filamentous dermatitis in canine Lyme disease. Methods and Results: Nine dogs were found to have cutaneous ulcerative lesions containing embedded or projecting dermal filaments. Spirochetes characterized as Borrelia spp. were detected in skin tissue by culture, histology, immunohistochemistry, polymerase chain reaction (PCR) and gene sequencing performed at five independent laboratories. Borrelia DNA was detected either directly from skin specimens or from cultures inoculated with skin specimens taken from the nine canine study subjects. Amplicon sequences from two canine samples matched gene sequences for Borrelia burgdorferi sensu stricto. PCR amplification failed to detect spirochetes in dermatological specimens from four healthy asymptomatic dogs. Conclusions: Our study provides evidence that a filamentous dermatitis analogous to Morgellons disease may be a manifestation of Lyme disease in domestic dogs.

Keywords: Morgellons disease; Lyme disease; Borrelia burgdorferi; Spirochetes; Dermopathy; Borrelial dermatitis; Dogs

From this link: https://www.scitechnol.com/peer-review/canine-filamentous-dermatitisassociated-with-borrelia-infection-1Qxf.php?article_id=5548

==============================
Many Blessings,
CrystalRiver



RMN is an RA production.

Articles In This Thread

Morgellons Disease: A Chemical and Light Microscopic Study
CrystalRiver -- Wednesday, 13-Jan-2021 05:52:35
Morgellons disease: a filamentous borrelial dermatitis
CrystalRiver -- Wednesday, 13-Jan-2021 05:52:35
Canine Filamentous Dermatitis Associated with Borrelia Infection
CrystalRiver -- Wednesday, 13-Jan-2021 05:52:35
Human strain of mad cow disease found in skin - study
CrystalRiver -- Wednesday, 13-Jan-2021 05:52:35
Did the U.S. Army help spread Morgellons and other diseases?
CrystalRiver -- Wednesday, 13-Jan-2021 05:52:35

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AN EXPLANATION OF THE FACTIONS